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Alendronic acid administration — GPhC CRA MCQ

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EasyPatient CounsellingAlendronic acid administrationGPhC CRA

A 72-year-old woman has been started on alendronic acid 70 mg once weekly for osteoporosis. She asks how to take it correctly. What is the most appropriate advice?

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Correct answer: D — Take on an empty stomach first thing in the morning with a full glass of plain water, then remain upright and do not eat for at least 30 minutes

Alendronic acid must be taken first thing in the morning on an empty stomach with a full glass of plain water (not mineral water, tea, coffee, juice, or milk). The patient must remain upright (sitting or standing) for at least 30 minutes and must not eat or drink anything other than water during this time. These instructions are essential to ensure adequate absorption and to reduce the risk of oesophageal irritation and ulceration.

Reference: BNF