SSRI counselling — GPhC CRA MCQ
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Correct answer: D — It may take four to six weeks before you notice a full improvement in your symptoms
SSRIs such as sertraline typically take four to six weeks to reach full therapeutic effect, although some improvement may be noticed earlier. Patients should be counselled about this delay in onset to set realistic expectations and encouraged to continue treatment even if they do not feel immediate benefit. Side effects such as nausea and anxiety may occur initially and often settle within the first two weeks.
Reference: BNF; NICE CKS Depression