skip to main content

UTI in pregnancy — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateInfection TherapeuticsUTI in pregnancyGPhC CRA

A 28-year-old woman presents to the pharmacy with a prescription for nitrofurantoin 100 mg modified-release twice daily for 3 days. She mentions she is 36 weeks pregnant and has symptoms of an uncomplicated lower urinary tract infection. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Contact the prescriber as nitrofurantoin should be avoided at term

Nitrofurantoin should be avoided at term (from 36 weeks gestation) due to the risk of neonatal haemolysis. The prescriber should be contacted to discuss an alternative such as a cefalosporin. Trimethoprim is also generally avoided in pregnancy due to its folate antagonist properties. Delaying treatment is inappropriate in pregnancy where UTIs carry a higher risk of complications.

Reference: BNF; NICE NG109 UTI