A 42-year-old man with epilepsy well-controlled on lamotrigine 200 mg twice daily presents with a prescription for lamotrigine from a different

Question

A 42-year-old man with epilepsy well-controlled on lamotrigine 200 mg twice daily presents with a prescription for lamotrigine from a different manufacturer than he usually receives. He asks if it matters. What is the most appropriate advice?

Accepted Answer

Lamotrigine is a Category 1 anti-epileptic and the same manufacturer's product should be maintained where possible

Answer

He should take a double dose on the first day of the new brand to ensure equivalent plasma levels

Answer

The new manufacturer may be cheaper and just as effective so he should switch

Answer

He can switch manufacturers freely as long as the dose remains the same

Answer

All lamotrigine tablets are identical so the manufacturer does not matter

AED manufacturer switching — GPhC CRA MCQ

A 42-year-old man with epilepsy well-controlled on lamotrigine 200 mg twice daily presents with a prescription for lamotrigine from a different manufacturer than he usually receives. He asks if it matters. What is the most appropriate advice?