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Dyspepsia red flags — GPhC CRA MCQ

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EasyGI TherapeuticsDyspepsia red flagsGPhC CRA

A 45-year-old man presents to the pharmacy requesting omeprazole 20 mg over the counter. He reports heartburn occurring most days for the past six weeks. He has lost half a stone in weight unintentionally. He has no difficulty swallowing. What is the most appropriate action?

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Correct answer: BRefuse the sale and refer urgently to the GP for further investigation, given unintentional weight loss with persistent dyspepsia

Unintentional weight loss combined with persistent dyspepsia in a patient over 40 years old is a red flag for possible upper GI malignancy. NICE recommends urgent referral for endoscopy (two-week wait pathway) for patients with dyspepsia and alarm symptoms such as unintentional weight loss, dysphagia, persistent vomiting, or GI bleeding. OTC supply of a PPI would be inappropriate as it could mask symptoms and delay diagnosis.

Reference: NICE NG12 Suspected Cancer; NICE CKS Dyspepsia