Dyspepsia red flags — GPhC CRA MCQ
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Correct answer: B — Refuse the sale and refer urgently to the GP for further investigation, given unintentional weight loss with persistent dyspepsia
Unintentional weight loss combined with persistent dyspepsia in a patient over 40 years old is a red flag for possible upper GI malignancy. NICE recommends urgent referral for endoscopy (two-week wait pathway) for patients with dyspepsia and alarm symptoms such as unintentional weight loss, dysphagia, persistent vomiting, or GI bleeding. OTC supply of a PPI would be inappropriate as it could mask symptoms and delay diagnosis.
Reference: NICE NG12 Suspected Cancer; NICE CKS Dyspepsia