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SGLT2 inhibitor counselling — GPhC CRA MCQ

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EasyEndocrine TherapeuticsSGLT2 inhibitor counsellingGPhC CRA

A 42-year-old woman collects a prescription for dapagliflozin 10 mg once daily, which has been added to her metformin 1 g twice daily for type 2 diabetes. She asks what side effects to look out for. What is the most important counselling point?

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Correct answer: E — She should be aware of signs of urinary tract and genital infections and maintain good hygiene

SGLT2 inhibitors such as dapagliflozin work by promoting glycosuria, which increases the risk of urinary tract infections and genital mycotic infections (thrush). Patients should be counselled to maintain good genital hygiene and seek medical attention if symptoms develop. SGLT2 inhibitors are typically associated with modest weight loss rather than gain, do not cause cough (an ACE inhibitor side effect), and are not associated with photosensitivity.

Reference: BNF; NICE NG28 Type 2 Diabetes