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Metronidazole-alcohol interaction — GPhC CRA MCQ

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EasyInfection TherapeuticsMetronidazole-alcohol interactionGPhC CRA

A 32-year-old woman presents a prescription for metronidazole 400 mg three times daily for 7 days for a dental abscess. She asks whether she can continue drinking alcohol during the course. What is the most appropriate advice?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — She should avoid alcohol during treatment and for at least 48 hours after finishing the course

Metronidazole can cause a disulfiram-like reaction with alcohol, leading to nausea, vomiting, flushing, and abdominal cramps. Patients should be advised to avoid alcohol during treatment and for at least 48 hours after completing the course to allow full elimination of the drug. This applies to all formulations of metronidazole, not just intravenous.

Reference: BNF Metronidazole