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DOAC Cancer VTE — SCE Medical Oncology MCQ

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ModerateOncological EmergenciesDOAC Cancer VTESCE Medical Oncology

A patient with cancer-associated venous thromboembolism has an unresected luminal gastric cancer that bleeds intermittently. What most strongly influences the choice between a DOAC and LMWH?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — The high gastrointestinal bleeding risk

DOACs are effective for many cancer-associated thromboembolic events, but an actively bleeding luminal gastrointestinal tumour substantially changes the benefit–harm balance. LMWH may be preferred while bleeding risk is high. Renal function, platelet count, interactions, tumour site and patient preference all require review.

Reference: https://www.nice.org.uk/guidance/ng158