Post-op RT Pathological Fracture — SCE Medical Oncology MCQ
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Correct answer: E — Treat the fixed site with 8 Gy once or 20 Gy in 5 fractions, guided by prognosis and rehabilitation goals
Explanation lettering: C = shown as A · D = shown as B · A = shown as C · E = shown as D · B = shown as E
B is correct. RCR guidance lists 8 Gy in one fraction or 20 Gy in five fractions after fixation of bone metastases; treatment choice considers persistent pain, rehabilitation goals, performance status and predicted survival. A omits local tumour control and palliation in a patient who remains symptomatic. C turns one acceptable multifraction approach into a universal longer course and unnecessarily irradiates the whole bone. D is not a substitute for local postoperative treatment of a fixed lesion. E disregards wound recovery and invents routine repeat irradiation. Field design should cover relevant metastatic and operative disease while respecting normal tissue.
Reference: Royal College of Radiologists radiotherapy dose-fractionation guidance: https://www.rcr.ac.uk/media/fezluddf/rcr-publications_radiotherapy-dose-fractionation-third-edition_march-2019.pdf