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FN Antibiotic 1-hour — SCE Medical Oncology MCQ

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EasyOncological EmergenciesFN Antibiotic 1-hourSCE Medical Oncology

A 62-year-old woman on chemotherapy develops febrile neutropenia. Her oncologist uses NICE CG151. What is the recommended empiric antibiotic and door-to-needle time?

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Correct answer: D — IV piperacillin-tazobactam (or local protocol equivalent) within 1 hour — NICE CG151 mandates antibiotic administration within 1 hour of presentation for neutropenic sepsis

NICE CG151: empiric IV beta-lactam (piperacillin-tazobactam per most UK protocols) within 1 hour of presentation. Door-to-needle time is a quality measure. Aminoglycoside added for septic shock. Glycopeptide for suspected line infection.

Reference: NICE CG151; ESMO Supportive Care