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Acral Melanoma Molecular — SCE Medical Oncology MCQ

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HardMelanoma & SkinAcral Melanoma MolecularSCE Medical Oncology

A fit man with metastatic castration-resistant prostate cancer progresses after docetaxel and is selected for cabazitaxel. Which starting regimen matches the UK SmPC?

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Correct answer: C — Give 25 mg/m² IV three-weekly with prednisone or prednisolone 10 mg daily

The UK SmPC regimen is cabazitaxel 25 mg/m² by one-hour IV infusion every three weeks with oral prednisone or prednisolone 10 mg daily throughout treatment. The other schedules alter dose, interval or steroid exposure and are not the labelled regimen tested here.

Reference: Cabazitaxel 20 mg/ml UK SmPC. https://www.medicines.org.uk/emc/product/14575/smpc