A rectal cancer has a complete clinical and radiological response after neoadjuvant treatment. The patient prefers watch-and-wait rather than total

Question

A rectal cancer has a complete clinical and radiological response after neoadjuvant treatment. The patient prefers watch-and-wait rather than total mesorectal excision. Which consent statement is most accurate under NICE NG151?

Accepted Answer

Explain uncertain outcomes, substantial local-regrowth risk and the need for expert watch-and-wait surveillance

Answer

Explain that choosing watch-and-wait precludes later salvage surgery if local regrowth is detected during surveillance

Answer

Explain that annual serum CEA is sufficient surveillance after complete clinical and radiological response

Answer

Explain that complete clinical response establishes cure and permits follow-up no more intensive than after polypectomy

Answer

Explain that watch-and-wait and surgery have equivalent established outcomes across all tumour and patient risk groups

Li-Fraumeni Surveillance — SCE Medical Oncology MCQ

A rectal cancer has a complete clinical and radiological response after neoadjuvant treatment. The patient prefers watch-and-wait rather than total mesorectal excision. Which consent statement is most accurate under NICE NG151?