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Molar Pregnancy Follow-up — SCE Medical Oncology MCQ

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HardGynaecological CancersMolar Pregnancy Follow-upSCE Medical Oncology

A patient with metastatic breast cancer develops new bilateral leg weakness, a sensory level and urinary retention. MRI is being arranged urgently for suspected metastatic spinal cord compression. What corticosteroid regimen should be started now under NICE NG234?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Dexamethasone 16 mg as soon as possible, then 16 mg daily while awaiting surgery or radiotherapy

Option D is correct because neurological signs of MSCC require immediate dexamethasone 16 mg and continuation at 16 mg daily while definitive treatment is arranged. Option C is subtherapeutic and stops prematurely. Option E is not the recommended regimen. Option B is an unnecessary pulse strategy, and option A risks irreversible neurological harm by delaying treatment.

Reference: NICE NG234: metastatic spinal cord compression. https://www.nice.org.uk/guidance/ng234/chapter/recommendations