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Stage II Colon Adjuvant — SCE Medical Oncology MCQ

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HardGI CancersStage II Colon AdjuvantSCE Medical Oncology

A fit 68-year-old has newly diagnosed metastatic hormone-sensitive prostate cancer with high-volume bone and liver disease. He has no major cardiovascular contraindication. Which principle should guide initial systemic treatment?

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Correct answer: B — Androgen-deprivation therapy combined with upfront treatment intensification

Fit patients with metastatic hormone-sensitive prostate cancer should generally receive androgen-deprivation therapy plus treatment intensification, using an androgen-receptor pathway inhibitor, docetaxel, or selected triplet therapy according to disease burden, fitness and comorbidity. Delaying intensification until castration resistance sacrifices an established survival benefit.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/cancer