After surgery and chemotherapy, a postmenopausal patient has ER-positive, HER2-negative early breast cancer with 2 positive axillary nodes, a 3.2 cm

Question

After surgery and chemotherapy, a postmenopausal patient has ER-positive, HER2-negative early breast cancer with 2 positive axillary nodes, a 3.2 cm grade 3 primary and no distant disease. Which feature set makes adjuvant abemaciclib with endocrine therapy eligible under NICE TA810?

Accepted Answer

Eligible: 2 positive nodes plus a grade 3 primary

Answer

Eligible: node-negative disease plus a grade 3 primary

Answer

Eligible: node-negative disease plus a 5.5 cm primary

Answer

Eligible: 2 positive nodes plus grade 2 and a 3.2 cm primary

Answer

Eligible: 2 positive nodes plus Ki-67 of 10%

Vulval Melanoma — SCE Medical Oncology MCQ

After surgery and chemotherapy, a postmenopausal patient has ER-positive, HER2-negative early breast cancer with 2 positive axillary nodes, a 3.2 cm grade 3 primary and no distant disease. Which feature set makes adjuvant abemaciclib with endocrine therapy eligible under NICE TA810?