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Breast Cancer — SCE Medical Oncology MCQ

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EasyBreast CancerBreast CancerSCE Medical Oncology

A 70-year-old woman on anastrozole develops progressive arthralgia limiting daily activities. She is reluctant to stop endocrine therapy. What management is appropriate?

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Correct answer: E — Switch AI or switch to tamoxifen; consider exercise programme and analgesia

AI-associated musculoskeletal syndrome affects 30-50%. Management: switch between AIs, switch to tamoxifen, exercise (strongest evidence), NSAIDs/paracetamol. Maintaining compliance is key.

Reference: ESMO 2024 Early Breast Cancer Guidelines; NICE NG101