Chemotherapy Toxicity — SCE Medical Oncology MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: A — Palonosetron, an NK1 antagonist, dexamethasone and olanzapine
Cisplatin is highly emetogenic. Current MASCC/ESMO guidance recommends four-drug prophylaxis: a 5-HT3 antagonist, NK1 antagonist, dexamethasone and olanzapine. The previous three-drug formulation omitted olanzapine and was no longer current.
Reference: 2023 MASCC and ESMO consensus recommendations for highly emetogenic chemotherapy (Published December 2023): https://pmc.ncbi.nlm.nih.gov/articles/PMC10739516/