Adrenaline Emergency Kit Formulation — MFDS Part 1 MCQ

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EasyPharmacologyAdrenaline Emergency Kit FormulationMFDS Part 1

Which adrenaline preparation should be immediately available in a UK dental practice emergency drug kit for the initial treatment of anaphylaxis?

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Correct answer: D — 1 mg/mL (1:1000) solution for intramuscular injection

The correct preparation is adrenaline 1 mg/mL (1:1000) for intramuscular injection. SDCEP specifies that dental practices should have 1 mL ampoules or pre-filled syringes of this preparation immediately available. For an adult with anaphylaxis, 0.5 mg—0.5 mL of the 1 mg/mL solution—is injected into the anterolateral thigh. Adrenaline 0.1 mg/mL (1:10,000) is not recommended for intramuscular treatment and intravenous adrenaline is reserved for appropriately experienced specialists with continuous monitoring. Adrenaline in a local anaesthetic cartridge is formulated for dental anaesthesia, not emergency treatment of anaphylaxis. Subcutaneous administration is less effective because adrenaline-induced vasoconstriction delays absorption.

Reference: Scottish Dental Clinical Effectiveness Programme, Practice Support Manual: Medical emergency drugs, current online guidance. https://www.psm.sdcep.org.uk/topics/medical-emergencies-and-life-support/medical-emergency-drugs/