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Pyogenic Granuloma Histological Name — MFDS Part 1 MCQ

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ModerateOral PathologyPyogenic Granuloma Histological NameMFDS Part 1

An excised gingival mass shows lobular aggregates of capillary-sized blood vessels within an oedematous, inflamed stroma. Which common oral lesion is classically associated with this lobular capillary haemangioma pattern?

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Correct answer: C — Pyogenic granuloma

The correct answer is C, pyogenic granuloma. Its characteristic histological pattern is lobular capillary haemangioma: lobular aggregates of proliferating capillary-sized vessels in an oedematous, inflamed stroma, often with surface ulceration. The name pyogenic granuloma is a misnomer because the lesion is neither pus-producing nor a true granulomatous inflammation. Not every pyogenic granuloma displays a fully developed lobular pattern, so this is best regarded as its characteristic histological pattern rather than an invariable synonym. A fibrous epulis and a fibroma are predominantly collagenous lesions. A peripheral giant cell granuloma contains numerous osteoclast-like multinucleated giant cells in a haemorrhagic stroma. A papilloma shows papillary proliferation of stratified squamous epithelium rather than lobular capillary proliferation.

Reference: Amritha R, Rahul M, Jot K, Tewari N. Unusual clinical presentation, microscopy and immunohistochemistry of oral pyogenic granuloma in a paediatric patient. BMJ Case Reports. 2024. https://pubmed.ncbi.nlm.nih.gov/39174046/