Carmellose Paste — MFDS Part 1 MCQ

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EasyPharmacologyCarmellose PasteMFDS Part 1

Which topical preparation acts primarily as a mucoadhesive covering agent, forming a protective barrier over an aphthous ulcer to reduce contact pain?

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Correct answer: D — Carmellose and gelatin oromucosal paste (Orabase)

Carmellose and gelatin oromucosal paste (Orabase) is the correct answer. It adheres to the oral mucosa and acts as a covering agent, providing mechanical protection from friction and reducing contact pain, particularly during eating. Chlorhexidine gel is an antiseptic and can be used in the management of aphthous ulceration, but its primary action is not formation of a protective barrier. Benzydamine provides local analgesic and anti-inflammatory relief without acting primarily as a mucoadhesive covering. Miconazole oral gel treats oral candidosis, while sodium fluoride varnish is used principally for caries prevention.

Reference: University College London Hospitals NHS Foundation Trust, Recurrent aphthous stomatitis ulcers, Treatment section, updated 28 May 2026. https://www.uclh.nhs.uk/patients-and-visitors/patient-information-pages/aphthous-ulcers