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Peripheral Ameloblastoma — MFDS Part 1 MCQ

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ModerateOral PathologyPeripheral AmeloblastomaMFDS Part 1

Which feature most reliably distinguishes a peripheral ameloblastoma from a central ameloblastoma?

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Correct answer: AIt arises primarily in gingival or alveolar mucosal soft tissue and lacks true intraosseous invasion

Peripheral ameloblastoma is the extraosseous counterpart of central ameloblastoma. It arises principally in the gingiva or alveolar mucosa and usually shows less aggressive behaviour, without true invasion of medullary bone. Superficial cupping or saucerisation of the underlying alveolar crest may occur through pressure and does not by itself establish a central origin. A central ameloblastoma originates within bone; cortical perforation with secondary soft-tissue extension therefore describes option B rather than a true peripheral lesion. Peripheral ameloblastoma does not have a higher recurrence risk and is not defined by malignancy or metastasis. Conservative local excision is generally appropriate, but recurrence is possible, so prolonged follow-up is recommended.

Reference: Anpalagan A et al. Current practice in the management of peripheral ameloblastoma: a structured review. British Journal of Oral and Maxillofacial Surgery. 2021;59(1):e1-e8. https://pubmed.ncbi.nlm.nih.gov/33162201/