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Tranexamic Acid Mouthwash Dose — MFDS Part 1 MCQ

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EasyPharmacologyTranexamic Acid Mouthwash DoseMFDS Part 1

A patient's medical practitioner has prescribed unlicensed tranexamic acid 5% mouthwash following a dental extraction, as an adjunct to local haemostatic measures. Which is the usual administration instruction?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Use 5–10 mL up to four times daily; rinse for 2 minutes, then spit out

The correct answer is D. Tranexamic acid is an antifibrinolytic that reduces local clot breakdown. For a 5% mouthwash, a usual UK hospital instruction is 5–10 mL up to four times daily, rinsed around the mouth for two minutes and then spat out; the prescriber determines the duration. It should not be swallowed intentionally. The other options give an incorrect volume, frequency, rinsing time or route of disposal. In UK dental practice, tranexamic acid mouthwash is an unlicensed preparation and is not a substitute for socket compression, packing or suturing. SDCEP does not advise routine primary-care dental prescribing for dental procedures, but states that mouthwash prescribed by the patient's medical practitioner may be used in addition to local haemostatic measures.

Reference: Worcestershire Acute Hospitals NHS Trust, Tranexamic Acid Mouthwash 5%, version 2.1, approved 2019: https://www.worcsacute.nhs.uk/documents/documents/patient-information-leaflets-a-z/waht-pi-0898-tranexamic-acid-mouthwash-5-percent-v2-1/?layout=file