Oral Verruca Vulgaris — MFDS Part 1 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateOral PathologyOral Verruca VulgarisMFDS Part 1

A child with common warts on the hands develops a solitary, painless, sessile papillary lesion of the oral mucosa. Biopsy confirms oral verruca vulgaris. Which HPV types are classically associated with this lesion?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — HPV 2 and 4

The correct answer is E: HPV 2 and 4. Oral verruca vulgaris represents the oral counterpart of the common cutaneous wart and may arise through autoinoculation from hand lesions. HPV types 2 and 4 are the types classically associated with it, although other cutaneous genotypes have occasionally been detected. HPV 6 and 11 are more characteristically associated with oral squamous papilloma and condyloma acuminatum. HPV 16 and 18 are high-risk oncogenic types, particularly relevant to HPV-associated oropharyngeal carcinoma rather than a common wart. HPV 31 and 33 are also high-risk types. HPV 1 is principally associated with plantar and palmoplantar warts and is not the classic oral verruca vulgaris pairing.

Reference: Syrjänen S. Human papillomavirus infections and oral tumors. Medical Microbiology and Immunology. 2003;192(3):123–128. https://pubmed.ncbi.nlm.nih.gov/12920585/