Papilloma Treatment — MFDS Part 1 MCQ
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Correct answer: A — Conservative complete surgical excision
The correct answer is A. A solitary oral squamous papilloma is a benign epithelial lesion for which conservative complete surgical excision is the standard definitive management. Excision also provides tissue for histopathological confirmation because papillomatous malignant and other benign lesions may have a similar clinical appearance. Recurrence after adequate excision is generally uncommon. Radical excision with wide oncological margins is unnecessary for a histologically benign papilloma. Radiotherapy and systemic chemotherapy are not indicated for this localised benign lesion and would cause disproportionate morbidity. Observation alone does not establish the diagnosis histologically and leaves the lesion untreated, so it is not the preferred definitive approach for a small, readily excisable lesion.
Reference: Anaya-Saavedra G, Castillejos-García I, Vázquez-Garduño M. Diagnostic challenges and clinical management gaps in HPV-related oral lesions. Frontiers in Oral Health. 2026. https://pubmed.ncbi.nlm.nih.gov/31232385/