Coeliac Disease Oral Features — MFDS Part 1 MCQ

Instant feedback + full explanation. One question, done properly.

ModerateHuman DiseaseCoeliac Disease Oral FeaturesMFDS Part 1

Which combination of oral findings is most characteristically associated with coeliac disease?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Developmental enamel defects and recurrent aphthous ulceration

Coeliac disease is associated with developmental enamel defects and recurrent aphthous ulceration. The enamel defects classically affect corresponding teeth symmetrically and follow a chronological pattern, reflecting disruption during enamel formation. NICE identifies dental enamel defects and severe or persistent mouth ulcers as findings that should prompt consideration of coeliac serology. Generalised gingival enlargement with petechiae suggests a haematological disorder or drug effect. Bilateral parotid enlargement is more typical of salivary gland, autoimmune or HIV-related disease. Oral hairy leukoplakia with candidosis indicates immunosuppression, while diffuse pigmentation with perioral freckling suggests a pigmentary syndrome such as Peutz–Jeghers syndrome.

Reference: National Institute for Health and Care Excellence. Coeliac disease: recognition, assessment and management, recommendations 1.1.1–1.1.2. NICE guideline NG20, 2015 (reviewed 2019). https://www.nice.org.uk/guidance/ng20/chapter/Recommendations