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Ehlers-Danlos Dental Relevance — MFDS Part 1 MCQ

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ModerateHuman DiseaseEhlers-Danlos Dental RelevanceMFDS Part 1

Which combination of clinical features is most characteristic of Ehlers-Danlos syndrome and particularly relevant when providing dental care?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EGeneralised joint hypermobility, fragile oral tissues and temporomandibular joint hypermobility or subluxation

Ehlers-Danlos syndromes are inherited connective-tissue disorders characterised by joint hypermobility and variable tissue fragility. In dentistry, fragile oral tissues may bruise, tear or heal poorly, while laxity of the temporomandibular joint can cause hypermobility, subluxation or dislocation during prolonged or excessive mouth opening. Therefore, A is the best answer. Recurrent fractures, blue sclerae and dentinogenesis imperfecta suggest osteogenesis imperfecta. Xerostomia with keratoconjunctivitis sicca and parotid enlargement suggests Sjögren syndrome. Macroglossia, hypotonia and a single transverse palmar crease are associated with Down syndrome. Micrognathia, glossoptosis and a U-shaped cleft palate constitute the Pierre Robin sequence.

Reference: Ben Mouna L, et al. Ehlers-Danlos syndrome: Role of the dentist. Archives de Pédiatrie. 2021. https://pubmed.ncbi.nlm.nih.gov/34583919/