Fibrous Epulis — MFDS Part 1 MCQ
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Correct answer: E — Reactive proliferation of gingival connective tissue following chronic local irritation
Explanation lettering: C = shown as A · D = shown as B · E = shown as C · B = shown as D · A = shown as E
A is correct. A fibrous epulis is a localised reactive hyperplastic lesion of gingival connective tissue, commonly associated with persistent local irritation such as calculus, plaque-retentive restoration margins or trauma. The firm pink appearance and collagenised connective tissue with mild chronic inflammation support a mature fibrous response. It is not a true epithelial neoplasm, excluding B, and viral epithelial proliferation would more typically produce a papillary or verrucous lesion, excluding C. Autoimmune periodontal disease causes inflammatory tissue destruction rather than a focal fibrous mass, excluding D. Hormonal influences can modify some reactive gingival lesions, particularly pregnancy-associated pyogenic granuloma, but fibrous epulis is neither confined to puberty nor primarily hormone-driven, excluding E.
Reference: Gu W, Li S, Hu S, et al. Epulis: A Narrative Review of Epidemiology, Clinical Features, Pathogenesis, and Management. Oral Health & Preventive Dentistry. 2025;23:507-524. https://pubmed.ncbi.nlm.nih.gov/40899761/