Lactobacillus and Caries — MFDS Part 1 MCQ

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ModerateMicrobiologyLactobacillus and CariesMFDS Part 1

In the traditional microbiological model of coronal dental caries, increased numbers of acidogenic and aciduric lactobacilli are most strongly associated with which stage of the carious process?

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Correct answer: E — Progression of an established lesion into dentine

Lactobacilli are classically associated with progression of an established carious lesion into dentine. Their strong acid production and ability to tolerate a low pH allow them to thrive in the acidic, retentive environment of a cavitated lesion. They are therefore regarded mainly as secondary contributors or enhancers of lesion progression rather than the principal initiators of enamel caries. Initial enamel demineralisation is produced by a dysbiotic cariogenic biofilm and has traditionally been associated more strongly with mutans streptococci. Lactobacilli do not promote lesion arrest or maintain a health-associated biofilm. Although they may be detected in root caries, initial colonisation of a newly exposed root surface is not their characteristic role.

Reference: Conrads G, About I. Pathophysiology of Dental Caries. Monographs in Oral Science. 2018;27:1–10. https://pubmed.ncbi.nlm.nih.gov/29794423/