Felypressin — MFDS Part 1 MCQ
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Correct answer: D — Prilocaine 3%
The correct answer is **A, prilocaine 3%**. In UK dentistry, felypressin is formulated with prilocaine 3%, commonly known as Citanest with Octapressin. Felypressin is a synthetic vasopressin analogue that produces local vasoconstriction and can be useful when adrenaline is to be avoided. Lidocaine 2% and articaine 4% dental cartridges are normally combined with adrenaline. Mepivacaine 3% is supplied as a plain solution without a vasoconstrictor, although a lower-strength mepivacaine preparation with adrenaline is also available. Bupivacaine is a long-acting local anaesthetic but is not the UK dental cartridge formulation paired with felypressin. The original answer was therefore correct, but the explanation and non-UK textbook reference required replacement with current, directly supportive UK material.
Reference: NHS Specialist Pharmacy Service, Managing reactions to dental local anaesthetic injections, section ‘Contents of dental LA cartridges’, updated 30 July 2024. https://sps.nhs.uk/articles/managing-reactions-to-dental-local-anaesthetic-injections/