Chlorhexidine Side Effects — MFDS Part 1 MCQ

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EasyPharmacologyChlorhexidine Side EffectsMFDS Part 1

Which preparation used in dentistry is most characteristically associated with reversible brown staining of the teeth and a burning sensation in the mouth on initial use?

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Correct answer: B — Chlorhexidine mouthwash

Chlorhexidine mouthwash is correct. It can cause reversible extrinsic discolouration of the teeth, tongue and some restorations. Transient taste disturbance and a burning sensation, particularly involving the tongue, may occur when treatment is started and usually diminish with continued use. Staining is not permanent, although professional scaling and polishing may occasionally be required. Metronidazole commonly causes a metallic taste but is not characteristically associated with brown tooth staining and oral burning. Amoxicillin is more commonly associated with gastrointestinal upset or hypersensitivity. Paracetamol and ibuprofen are analgesics and do not produce this characteristic combination of local oral adverse effects.

Reference: Thornton & Ross Ltd. Care Chlorhexidine Digluconate 0.2% w/v Antiseptic Mouthwash, Summary of Product Characteristics, section 4.8 Undesirable effects. Updated 12 January 2024. https://www.medicines.org.uk/emc/product/4818/smpc