Behcet Disease — MFDS Part 1 MCQ

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ModerateOral MedicineBehcet DiseaseMFDS Part 1

Which combination of recurrent clinical features constitutes the classic triad of Behçet disease?

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Correct answer: A — Oral aphthous ulceration, genital ulceration, and uveitis

Explanation lettering: E = shown as B · B = shown as E

A is correct. Behçet disease is a multisystem inflammatory vasculitis classically associated with recurrent oral aphthous ulcers, recurrent genital ulcers and ocular inflammation, particularly uveitis. This classic triad should not be mistaken for a complete modern diagnostic rule, because skin lesions, pathergy and other systemic manifestations may also contribute to diagnosis. Option B is more suggestive of systemic lupus erythematosus. Option C describes the sicca complex of Sjögren syndrome. Option D suggests significant cellular immunodeficiency, while option E describes Plummer–Vinson syndrome. In dental practice, recurrent oral ulceration accompanied by genital ulceration or ocular symptoms should prompt appropriate medical referral.

Reference: Tugal-Tutkun I, Gupta V, Cunningham ET. Behçet uveitis: Current practice and future perspectives. Frontiers in Medicine. 2022. https://pubmed.ncbi.nlm.nih.gov/36160151/