Anaphylaxis Management — MFDS Part 1 MCQ

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EasyHuman DiseaseAnaphylaxis ManagementMFDS Part 1

In a dental practice, which emergency drug should be administered first for suspected anaphylaxis?

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Correct answer: D — Adrenaline (epinephrine) 1 mg/mL (1:1000) intramuscularly

Intramuscular adrenaline (epinephrine) 1 mg/mL (1:1000) is the first-line drug for suspected anaphylaxis and should be given without delay. The preferred site is the anterolateral middle third of the thigh; the usual adult dose is 500 micrograms (0.5 mL), repeated after 5 minutes if life-threatening airway, breathing or circulatory features persist. Hydrocortisone is not a first-line or routine immediate treatment. Chlorphenamine may relieve persistent cutaneous symptoms after initial stabilisation but does not treat airway obstruction or shock. Salbutamol may be added for persistent bronchospasm but must not replace adrenaline. Buccal midazolam is used for prolonged convulsive seizures, not anaphylaxis. Call 999 and provide appropriate ABCDE supportive management, including oxygen.

Reference: electronic Medicines Compendium. Adrenaline (Epinephrine) Injection BP 1 in 1000, Summary of Product Characteristics, sections 4.1–4.2. Updated 23 June 2026. https://www.medicines.org.uk/emc/product/6284/smpc