Aphthous Ulceration — MFDS Part 1 MCQ
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Correct answer: E — Predominant involvement of keratinised mucosa, such as the attached gingiva and hard palate
A is the exception. Minor recurrent aphthous ulcers predominantly affect movable, non-keratinised lining mucosa, including the labial and buccal mucosa, floor of mouth and ventral tongue. Predominant involvement of the attached gingiva or hard palate is therefore not characteristic and should prompt consideration of alternatives such as recurrent intraoral herpes. Aphthous ulcers are typically painful and have a shallow yellowish-white base surrounded by an erythematous halo. Their episodic recurrence is a defining feature of recurrent aphthous stomatitis. The other options therefore describe characteristic clinical findings.
Reference: University College London Hospitals NHS Foundation Trust, Department of Oral Medicine. Recurrent aphthous stomatitis ulcers, updated 2026. https://www.uclh.nhs.uk/patients-and-visitors/patient-information-pages/aphthous-ulcers