Odontome — MFDS Part 1 MCQ
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Correct answer: C — Hamartomatous malformation
An odontome is biologically a hamartomatous malformation rather than a true neoplasm. It contains mature dental tissues native to the site, including enamel, dentine, cementum and pulp. In a compound odontome these tissues form multiple tooth-like structures, whereas in a complex odontome they form a disorganised mass. Although odontomes are conventionally included within classifications of benign odontogenic tumours, this does not make them true benign neoplasms because they lack autonomous neoplastic growth. They are neither malignant lesions nor cysts, although an odontome may occasionally be associated with a dentigerous cyst. They are developmental rather than inflammatory lesions.
Reference: DeColibus KA et al. Clinicoradiopathologic Analysis of Odontomas: A Retrospective Study of 242 Cases. Dent J (Basel). 2023;11(11):253. https://pubmed.ncbi.nlm.nih.gov/35312978/