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Stenotrophomonas Colonisation Bronchiectasis — SCE Infectious Diseases MCQ

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HardRespiratory InfectionStenotrophomonas Colonisation BronchiectasisSCE Infectious Diseases

A healthy non-pregnant adult presents 4 hours after a deep dog-bite puncture to the hand. The wound has been irrigated, is not infected and cannot be closed primarily. They had immediate anaphylaxis to penicillin. Which oral antibacterial prophylaxis follows NICE NG184?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: CDoxycycline 200 mg on day 1, then 100–200 mg daily, plus metronidazole 400 mg TDS for 3 days

Explanation lettering: B = shown as A · D = shown as B · A = shown as C · C = shown as D

A is correct. A deep puncture to the hand is a high-risk bite for which prophylaxis is appropriate; NICE gives doxycycline plus metronidazole as the first-choice oral alternative in penicillin allergy and specifies 3 days for prophylaxis. B lacks reliable anaerobic and Pasteurella coverage and uses a treatment-length course. C omits anaerobic cover and is unnecessarily prolonged. D is not the NICE adult alternative and exposes the patient to excess toxicity. E uses a cephalosporin after immediate anaphylaxis without the specialist advice NICE requires.

Reference: NICE NG184: human and animal bites: https://www.nice.org.uk/guidance/ng184/chapter/Recommendations