Stenotrophomonas Colonisation Bronchiectasis — SCE Infectious Diseases MCQ
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Correct answer: C — Doxycycline 200 mg on day 1, then 100–200 mg daily, plus metronidazole 400 mg TDS for 3 days
Explanation lettering: B = shown as A · D = shown as B · A = shown as C · C = shown as D
A is correct. A deep puncture to the hand is a high-risk bite for which prophylaxis is appropriate; NICE gives doxycycline plus metronidazole as the first-choice oral alternative in penicillin allergy and specifies 3 days for prophylaxis. B lacks reliable anaerobic and Pasteurella coverage and uses a treatment-length course. C omits anaerobic cover and is unnecessarily prolonged. D is not the NICE adult alternative and exposes the patient to excess toxicity. E uses a cephalosporin after immediate anaphylaxis without the specialist advice NICE requires.
Reference: NICE NG184: human and animal bites: https://www.nice.org.uk/guidance/ng184/chapter/Recommendations