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S. pneumoniae Gram Stain — SCE Infectious Diseases MCQ

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HardRespiratory InfectionS. pneumoniae Gram StainSCE Infectious Diseases

An adult with pneumonia has a non-purulent pleural effusion. Pleural pH is 7.28, LDH 1,140 IU/L, glucose 3.5 mmol/L and ultrasound shows septations; fever persists despite antibiotics. What does BTS guidance support?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BInsert an intercostal drain because intermediate pH plus LDH above 900 and septation indicate complicated infection

Explanation lettering: D = shown as A · C = shown as B · B = shown as C · E = shown as D · A = shown as E

C is correct. A pH above 7.2 but below 7.4 is intermediate risk, not reassuring; LDH above 900, low glucose, persistent fever, substantial fluid, CT enhancement or ultrasound septation strengthen the case for drainage. A and B ignore those modifiers. D jumps past initial tube drainage. E uses intrapleural therapy without an access route or initial drainage assessment.

Reference: BTS guideline for pleural disease 2023: https://thorax.bmj.com/content/78/Suppl_3/s1