LSIL in HIV Cervical Screening — SCE Infectious Diseases MCQ
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Correct answer: C — Rifampicin, dapsone and clofazimine for 6 months as WHO multidrug therapy
Explanation lettering: E = shown as A · C = shown as B · B = shown as C · A = shown as D · D = shown as E
B is correct. Since 2018 WHO has recommended the same three-drug MDT backbone—rifampicin, dapsone and clofazimine—for both classifications, for six months in paucibacillary and 12 months in multibacillary disease. A is the older two-drug PB regimen and is the key trap in this item. C is monotherapy and would select resistance. D is tuberculosis treatment. Baseline blood count, liver function and haemolysis risk are reviewed, but a normal G6PD result does not justify omitting toxicity surveillance. Nerve function is documented serially because reactions can cause irreversible disability even while bacillary treatment is effective.
Reference: WHO: guidelines for diagnosis, treatment and prevention of leprosy: https://www.who.int/publications/i/item/9789290226383