Blastomycosis — SCE Infectious Diseases MCQ

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HardFungal InfectionsBlastomycosisSCE Infectious Diseases

Histology from a chronic pulmonary and cutaneous syndrome shows large thick-walled yeast with broad-based budding. Which fungus is most likely?

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Correct answer: B — Blastomyces dermatitidis

The best answer is “Blastomyces dermatitidis”. Broad-based budding is the defining tissue morphology of Blastomyces; geography and culture support but do not replace histopathology and culture. Blastomyces is identified by broad-based budding yeast in tissue; geography and exposure support but do not replace histopathology and culture. UK specialist laboratories support identification and management of imported and invasive fungal disease using tissue morphology, culture and molecular methods.

Reference: Clinical review of blastomycosis: https://pmc.ncbi.nlm.nih.gov/articles/PMC5657236/ UKHSA fungal-infections guidance collection: https://www.gov.uk/government/collections/fungal-infections