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Sepsis Six — SCE Infectious Diseases MCQ

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HardAntimicrobial StewardshipSepsis SixSCE Infectious Diseases

A high-risk patient with suspected sepsis receives prompt empirical intravenous antibiotics after cultures are obtained without delaying treatment. Which documentation most directly supports antimicrobial stewardship?

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Correct answer: DDocument indication and review time, then narrow, switch or stop treatment

The best answer is “Document indication and review time, then narrow, switch or stop treatment”. Urgency and stewardship are compatible: the initial regimen is proportionate to risk, while explicit review using microbiology, source control and clinical trajectory prevents unnecessary broad exposure. Sepsis care combines urgent risk-stratified antimicrobials with cultures where this does not delay treatment and documented review, narrowing or stopping when evidence changes.

Reference: NICE NG253: suspected sepsis in people aged 16 or over: https://www.nice.org.uk/guidance/ng253/chapter/Recommendations