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Legionella Pneumonia — SCE Infectious Diseases MCQ

Instant feedback + full explanation. One question, done properly.

HardRespiratory InfectionLegionella PneumoniaSCE Infectious Diseases

A renal-transplant recipient with no history of hepatitis A infection or vaccination shared a household with a laboratory-confirmed hepatitis A case 8 days ago. They are asymptomatic and remain substantially immunosuppressed. Which UK post-exposure intervention is indicated?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Give hepatitis A vaccine now and arrange human normal immunoglobulin without delaying vaccination for serology

Explanation lettering: B = shown as A · D = shown as B · E = shown as D · A = shown as E

B is correct. This fully susceptible immunosuppressed close contact is within 14 days of exposure, so UKHSA recommends hepatitis A vaccine plus human normal immunoglobulin; testing may be useful but must not delay vaccination. A omits the passive protection recommended for this high-risk host. C omits active immunisation. D creates a clinically important delay. E substitutes surveillance for timely post-exposure prevention.

Reference: UKHSA: hepatitis A immunoglobulin post-exposure guidance: https://www.gov.uk/government/publications/immunoglobulin-when-to-use/hepatitis-a-immunoglobulin-issued-2024