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PJP in Non-HIV — SCE Infectious Diseases MCQ

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HardImmunocompromised HostPJP in Non-HIVSCE Infectious Diseases

A patient receiving dexamethasone-containing myeloma therapy develops progressive bilateral ground-glass pneumonia, high beta-D-glucan and cyst forms on BAL silver stain. What is the diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Pneumocystis jirovecii pneumonia

The best answer is “Pneumocystis jirovecii pneumonia”. Prolonged corticosteroid and haematological therapy create substantial PJP risk outside HIV; diffuse ground glass, elevated beta-D-glucan and characteristic cysts establish the diagnosis. BHIVA guidance governs investigation and treatment of HIV-associated disease and supports standard specialist care when HIV is virologically controlled.

Reference: BHIVA clinical guidelines: https://bhiva.org/clinical-guidelines/