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MRSA Screening — SCE Infectious Diseases MCQ

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HardInfection Prevention & ControlMRSA ScreeningSCE Infectious Diseases

A patient known to carry MRSA is listed for elective prosthetic-knee replacement. Which preoperative approach best reflects NICE surgical-site-infection guidance?

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Correct answer: B — Use nasal mupirocin plus chlorhexidine wash under a local protocol informed by resistance

For procedures in which S. aureus is a likely cause of surgical-site infection, NICE advises considering nasal mupirocin with chlorhexidine body wash, decided locally and with attention to resistance. It does not recommend rifampicin monotherapy, automatic cancellation until repeated negative screens, or universal decolonisation for every operation.

Reference: NICE NG125: Surgical site infections: https://www.nice.org.uk/guidance/ng125/chapter/Recommendations