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Behçet Disease — SCE Infectious Diseases MCQ

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EasySTIsBehçet DiseaseSCE Infectious Diseases

A 30-year-old woman presents with painful oral ulcers, genital ulcers, and bilateral anterior uveitis. She is of Turkish origin. Pathergy test is positive. What is the most likely diagnosis?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BBehçet disease

Recurrent oral ulcers, genital ulcers, and uveitis with a positive pathergy test in a patient from the Eastern Mediterranean 'Silk Road' region is classic for Behçet disease. This is a systemic vasculitis, not an infectious disease — the positive pathergy test (hyperreactivity to needle prick) is relatively specific. This is an important non-infectious mimic that ID clinicians must recognise. STI screening should still be performed to exclude co-existing infection.

Reference: BSR 2024 – Behçet disease guidelines; NICE CKS 2024 – Behçet disease