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Lyme Disease — SCE Infectious Diseases MCQ

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HardTravel Medicine & VaccinationLyme DiseaseSCE Infectious Diseases

A 67-year-old traveller with a history of thymoma needs a certificate for travel to a yellow-fever-risk country. What is the safest next step?

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Correct answer: BDo not administer yellow-fever vaccine routinely; obtain specialist risk assessment and consider a medical waiver plus mosquito-avoidance planning after review with review clinically-reassessed

The best answer is “Do not administer yellow-fever vaccine routinely; obtain specialist risk assessment and consider a medical waiver plus mosquito-avoidance planning after review with review clinically-reassessed”. Thymus disease increases serious live yellow-fever vaccine adverse-event risk, so exposure risk, entry rules and waiver options need specialist balancing. “Give vaccine immediately because certification overrides contraindications” is less appropriate because it conflicts with the clinical discriminator or cited guidance. “Use half-dose vaccine to eliminate viscerotropic risk” is less appropriate because it conflicts with the clinical discriminator or cited guidance. “Use doxycycline as a substitute vaccine certificate” is less appropriate because it conflicts with the clinical discriminator or cited guidance. “Give intravenous immunoglobulin with live vaccine” is less appropriate because it conflicts with the clinical discriminator or cited guidance.

Reference: NaTHNaC yellow-fever guidance: https://travelhealthpro.org.uk/factsheet/18/yellow-fever