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Fusobacterium Infection — SCE Infectious Diseases MCQ

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HardRespiratory InfectionFusobacterium InfectionSCE Infectious Diseases

A gardener with severe pneumonia, hyponatraemia and diarrhoea has a negative Legionella urinary antigen test. He frequently handles potting compost. Which test is most important next?

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Correct answer: BSend lower-respiratory material for Legionella PCR and culture across species and serogroups

Most urinary antigen assays primarily detect L. pneumophila serogroup 1. A negative result therefore does not exclude non-serogroup-1 L. pneumophila or other species such as L. longbeachae, which is associated with compost exposure. Lower-respiratory PCR and culture broaden detection and permit further characterisation.

Reference: UKHSA: Legionellosis in residents of England and Wales 2024: https://www.gov.uk/government/statistics/legionellosis-in-residents-of-england-and-wales-2024/legionellosis-in-residents-of-england-and-wales-2024