skip to main content

Lymphogranuloma Venereum — SCE Infectious Diseases MCQ

Instant feedback + full explanation. One question, done properly.

ModerateSTIsLymphogranuloma VenereumSCE Infectious Diseases

A 32-year-old sex worker presents with proctitis. She reports receptive anal intercourse. Rectal NAAT is positive for Chlamydia trachomatis serovar L2. What is the diagnosis and recommended treatment?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Lymphogranuloma venereum (LGV); Doxycycline 100 mg BD for 21 days

Chlamydia trachomatis serovars L1–L3 cause lymphogranuloma venereum (LGV), which presents with proctitis (rectal pain, discharge, tenesmus), inguinal lymphadenopathy, or genital ulceration. LGV requires a 21-day course of Doxycycline 100 mg BD, unlike non-LGV chlamydial infection which only requires 7 days. LGV has been increasing in the UK, particularly among MSM, but is seen in all populations. Rectal chlamydia should have LGV typing performed.

Reference: BASHH 2019 – LGV guidelines; UKHSA 2024 – LGV surveillance