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Ciclosporin PRES — SCE Dermatology MCQ

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HardDrug ReactionsCiclosporin PRESSCE Dermatology

A patient taking ciclosporin develops acute headache, visual disturbance, confusion and a blood pressure of 180/110 mmHg. MRI shows bilateral parieto-occipital vasogenic oedema. What is the diagnosis?

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Correct answer: B — Posterior reversible encephalopathy syndrome

Ciclosporin-associated hypertension and endothelial toxicity can precipitate posterior reversible encephalopathy syndrome. The parieto-occipital vasogenic oedema, encephalopathy and visual symptoms require urgent blood-pressure control and withdrawal or reduction of the precipitating agent.

Reference: https://academic.oup.com/bjd/pages/bad-guidelines