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Lichen Planus Histology — SCE Dermatology MCQ

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HardInflammatory DermatosesLichen Planus HistologySCE Dermatology

A lichenoid eruption begins after a new medication. Which histological feature favours a lichenoid drug reaction over idiopathic lichen planus?

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Correct answer: DParakeratosis with eosinophils in a deeper mixed infiltrate

Lichenoid drug reactions may show parakeratosis, a deeper perivascular component and eosinophils or plasma cells. The distinction is not absolute and requires clinicopathological correlation with medication timing and improvement after withdrawal.

Reference: https://academic.oup.com/bjd/pages/bad-guidelines