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Sarcoidosis — SCE Dermatology MCQ

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HardConnective Tissue & VasculitisSarcoidosisSCE Dermatology

A 55-year-old woman presents with painful red nodules on both shins. She has recently been diagnosed with sarcoidosis. What is the prognostic significance of erythema nodosum in sarcoidosis?

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Correct answer: E — A favourable, often self-limiting Löfgren-pattern clinical course

The best answer is “A favourable, often self-limiting Löfgren-pattern clinical course”. The diagnosis follows the defining morphology, distribution, histopathology and time course; management changes when red flags, scarring, systemic disease or malignancy risk are present. The alternatives “A pulmonary-fibrotic phenotype with a high progression risk”, “A neurosarcoidosis phenotype with a high disability risk”, “A cardiac-sarcoidosis phenotype with a high arrhythmia risk”, “A renal-sarcoidosis phenotype with a high failure risk” are clinically adjacent possibilities, but they do not fit the defining morphology, distribution, histopathology, risk signal or management sequence in this stem.

Reference: British Association of Dermatologists clinical resources: https://www.bad.org.uk/