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Melanoma — SCE Dermatology MCQ

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HardSkin CancerMelanomaSCE Dermatology

A sentinel lymph node from a patient with cutaneous melanoma contains a 0.05 mm cluster of morphologically confirmed melanoma cells. How is this classified in AJCC melanoma staging?

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Correct answer: C — Node-positive microscopic metastasis

Unlike breast-cancer staging, AJCC melanoma staging has no lower size threshold below which confirmed nodal melanoma cells are ignored. A tiny immunohistochemically or morphologically confirmed deposit makes the sentinel node positive and contributes to pathological N staging; tumour burden still has prognostic relevance.

Reference: https://www.nice.org.uk/guidance/ng14